>PHD STUDENTS

>José Almeida

 

ORCID: 0000-0003-2656-6443

SCOPUS ID: 57193757476

RESEARCHER IDV-6371-2018

emailj.almeida@fc.up.pt

PhD student of the Sustainable Chemistry doctoral program, Universidade do Porto.

MSc in Chemistry, 2017, Faculdade de Ciências da Universidade do Porto.

Thesis: “Novas abordagens na síntese de macrociclos porfírinicos para incorporação em polímeros” (“New approaches on the synthesis of porphyrinic macrocycles, for polymer incorporation”)

Keywords: organic synthesis, microwave-assisted synthesis, metal complexes, tetrapyrrolic macrocycles, optical sensors, UV-Vis and fluorescence spectroscopy, photodynamic therapy, smart polymers, metal-organic frameworks

I’m a Sustainable Chemistry PhD student and my work is focused on the development of new photosensitizers for photodynamic therapy. Some of the work objectives are: 1) the conjugation of porphyrins and hydroporphyrins with bioactive molecules and enzymatic inhibitors, which could be released in physiological media through a cleavable linker; 2) synthesis of new hydroporphyrins through mild and efficient protocols (e.g., by using microwave irradiation); 3) incorporation of porphyrins and hydroporphyrins in metal-organic frameworks, which would enhance significantly the therapeutic efficiency of PDT.

 

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