>Ana Margarida Silva
Area of scientific activity
Research interests in organic chemistry, particularly in the synthesis of porphyrinic macrocycles and analogues.
Synthesis of chelating ligands and their coordination complexes.
Design of colorimetric and fluorescent ligands with clinical and environmental applications.
Implementation of advanced synthetic methodologies based on the “green chemistry” concepts, including the use of microwave-assisted organic chemistry and the development of new heating processes based on Ohmic heating for perform organic synthesis in water.
Domain of specialization
organic chemistry, inorganic chemistry
Present research interest
Synthesis and characterization of new functionalized porphyrins.
Design of multi-functionalized molecules for applications in medicinal and environmental Chemistry.
Preparation of functional building blocks.
Advanced heating methodologies for chemical synthesis.
Design of new ligands for metal-organic frameworks (MOFs).
 Queirós, C., Leite, A., Cunha-Silva, L., de Castro, B., Rangel, M., Sousaraei, A., Cabanillas-Gonzalez, J., Gámez, F., Jamardo, E., Vargas, A.P., Moscoso, F.G., Lopes-Costa, T., Pedrosa, J.M., Silva, A.M.G., Synthesis and characterization of two fluorescent isophthalate rosamines: from solution to immobilization in solid substrates, Dyes Pigm. 2018, 157, 405-414.
 Almeida, J., Aguiar, A., Leite, A., Silva, A.M.N., Cunha-Silva, L., de Castro, B., Rangel, M., Barone, G., Tomé, A.C., Silva, A.M.G., 1,3-Dipolar cycloadditions with meso-tetraarylchlorins – site selectivity and mixed bisadducts, Org. Chem. Front., 2017, 4, 534 544.
 Queirós, C., Leite, A., Couto, M.G.M., Cunha-Silva, L., Barone, G., de Castro, B., Rangel, M., Silva, A.M.N., Silva, A.M.G., The influence of the amide linkage in the iron(III)-binding properties of catechol modified rosamine derivatives, Chem. Eur. J., 2015, 21, 15692–15704.
 Aguiar, A., Leite, A., Silva, A.M.N., Tomé, A.C., Cunha-Silva, L., de Castro, B., Rangel, M., Silva, A.M.G., Isoxazolidine-fused meso-tetraarylchlorins as key tools for the synthesis of mono- and bis-annulated chlorins, Org. Biomol. Chem., 2015, 13, 7131-7135.
 Pinto, J., Silva, V.L.M., Silva, A.M.G., Silva, A.M.S., Costa, J.C.S., Santos, L.M.N.B.F., Enes, R., Cavaleiro, J.A.S., Vicente, A.A.M.O.S., Teixeira, J.A.C., Ohmic heating as a new efficient process for organic synthesis in water, Green Chem., 2013, 15, 970–975.